Research Studies: Medial Meniscal Tear

Medial Meniscus Tear   

Healing of a medial meniscus tear (2007)

Fullerton BD. High-Resolution Ultrasound and Magnetic Resonance Imaging to Document Tissue Repair After Prolotherapy Arch PM&R 2008. 89(2):377-385

Dr. Reeves' Notes: The medial meniscus of the knee is non linear structure. Dr. Fullerton published examples of regeneration from dextrose injection, including an example of repair of a tear in the medial meniscus. Image B was actually taken after one injection and Image D after 3 injections, with the obvious tear closing in favor of meniscus tissue with normal appearance. The patient stopped having symptoms, the McMurray test became negative and the meniscus also healed according to pre and post MRI scans. 

A copy of the entire study is available in PDF format here.

An abstract of the study is available below here, with a copy of the content available below...

High-resolution ultrasound imaging of musculoskeletal tissue is increasing in popularity because of patient tolerability, low cost, ability to visualize tissue in real-time motion, and superior resolution of highly organized tissue such as a tendon. Prolotherapy, defined as the injection of growth factors or growth factor production stimulants to grow normal cells or tissue, has been a controversial procedure for decades; it is currently gaining in popularity among physiatrists and other musculoskeletal physicians. This report describes imaging of tendons, ligaments, and medial meniscus disease (from trauma or degeneration). Although these tissues have been poorly responsive to nonsurgical treatment, it is proposed that tissue growth and repair after prolotherapy in these structures can be documented with ultrasound and confirmed with magnetic resonance imaging. Directions for future research application are discussed.


K. Dean Reeves, M.D. is a physician and medical researcher in the area of pain caused by arthritis, chronic sprains and chronic strains. His private practice is located in the greater Kansas City area of Roeland Park, Kansas.  He collaborates in research with other locations across the country and internationally, and is licensed in the states of Kansas and Missouri.

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Dr. K. Dean Reeves

No part of this site should be understood to be personal medical advice or instruction in how to perform injection therapy. A decision on treatment requires a good history and full examination and a knowledge of your treatment goals. Treatment decisions should be made in consultation with your personal healthcare professional and/or prolotherapist.